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MiRNAs and LincRNAs


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

The differential expression of miRNA in cancer could be useful in diagnosis to distinguish between malignant and reactive lesions. Moreover, given that the complex mechanism of gene regulation by microRNAs is profoundly influenced by variations in gene sequence (polymorphisms) of the target sites; it may indicate that miRNA expression could be influenced not only by tumor type but also by individual variability related to ethnic geographical region. On the other hand, considering critical roles for chromatin-modifying complexes in the establishment and maintenance of cells pluripotency, and the possibility of lincRNAs interactions with these complexes could impart target specificity. LincRNAs (such as HOTAIR) could represent an additional layer of complexity in the networks controlling cellular differentiation. Finally, miRNA-based cancer therapy is a very interesting field of research that offers the appeal of targeting multiple gene networks controlled by a single miRNA.

Product Specifications
SKU :COC30127
AuthorRuth Zarate and Valentina Boni
Number of Pages96
Publishing Year4/23/2012
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-29 00:00:00