As we know that, there is a vast water crisis in the world due to less availability of potable water. A device which converts the saline water into drinkable water by use of solar energy is called solar still. many researchers have worked on solar still to improve performance but no one has applied CFD simulation approach. Here, hemispherical head solar still is made and tested in climate conditions of Mehsana, Gujarat to get better yield. All experimental results have compared with CFD simulation results. This CFD research also show step by step procedure applied to hemispherical solar still for simulation. we have found that there is a good agreement of CFD results and Experimental results. CFD is a very important tool for evaluating performance of solar energy applications.