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Modulation of the immune system by Listeria monocytogenes


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Early life exposure to a specific, live bacterial strain can reduce susceptibility to asthma. We confirmed this protective efficacy here, using the gold standard of in vivo airway hyper-reactivity. We also determined that a therapeutic Lm-vaccine based approach might provide benefit, but likely only after repeat immunization. While our findings suggested that Lm decreased a Th2 response, we here discovered that neonatal prophylactic Lm vaccination did not exacerbate the development of the Th-1/17 driven disease, HP. Together this argues that Lm immunization balances rather than biases immune ontogeny. This sets the framework to test multiple hypotheses on the mechanism of immune skewing towards or away from the development of asthma and other atopic diseases.

Product Specifications
SKU :COC84482
AuthorSheka Aloyouni
Number of Pages64
Publishing Year2013-05-15T00:00:00.000
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00