Remarkable developments and scope of MolecularBiology and Biotechnology for human welfare haveattracted huge number of talents to pursue theircareer in this field. Banasthali University,Rajasthan, India as part of its Jubilee Celebrationscommemorating 25 years of its establishment as a university, organized an International Conference on Molecular Biology and Biotechnology (ICMBB-2008) during October 19-21,2008. The conference received overwhelming response and was attended by more than 500 participants globally including delegates not only from India but also from USA, Japan, Australia, Austria, Belgium, Canada, Nigeria etc. Total 18 technical sessions, including two poster sessions were organized. These sessions included 14 keynote lectures, about 50 oral presentations and over 100 posters. Based on quality and interest of audience few full length papers/articles were invited from established and also from budding scientists to compile the present proceedings. We have tried to cover various aspects of biotechnology undertaken during the conference to make the proceedings attractive and interesting for wider groups of Biologists.