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Molecular mechanisms of melanoma antigen processing

 

Marketed By :  Scholars' Press   Sold By :  Kamal Books International  
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  • Product Description
 

Despite intensive research melanoma remains one of the most aggressive types of cancer by generating the most deadly form of skin tumour, characterized by a rapid metastatic progression. Recent studied have proved that metastatic cells tumour growth is induced by angiogenesis activation. One of the pro-angiogenic chemokine known to be involved in cancer processes is granulocyte chemotactic protein-2 (GCP-2). My work was dedicated to investigations of the effect of GCP-2 overexpression in B16F1 murine melanoma cells, on their tumorigenesis in vivo and invasive potential in vitro. Differences in the level of expression and secretion of this chemokine were correlated with Extracellular signal-regulated kinase (ERK1/2) phosphorylation status and found to modulate melanoma cell invasivity and pigmentation.

Product Specifications
SKU :COC53116
AuthorLivia Elena Sima
LanguageEnglish
BindingPaperback
Number of Pages272
Publishing Year2014-01-30T00:00:00.000
ISBN9783639702477
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandScholars' Press
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-06-08 00:00:00