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Molecular Staging of Colorectal Carcinoma


Marketed By :  VDM Verlag Dr. Müller   Sold By :  Kamal Books International  
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  • Product Description

Einführung in die Problemstellung: Colorectal carcinoma is one of the most common causes for cancer death in the western world. Newer investigations have lead to the discovering of molecular markers, such as Epidermal Growth Factor (EGF) and its receptor. Tissue samples of 268 patients, who had undergone surgery for colorectal cancer liver metastasis with curative intent, were analyzed for Epidermal Growth Factor 61 A/G polymorphism. Therefore real time PCR was used. Zusammenfassung des Buchinhaltes: Interestingly a 1,9 fold increased risk for recurrence was registered in male patients, who expressed the EGF G/G genotype. This study suggests that patients carrying the EGF G/G genotype have an increased risk of liver metastasis recurrence after curative surgery. In future, such molecular parameters as EGF could be used to improve staging systems and also to calculate the individual risk profiles after surgery in a more reliable way.

Product Specifications
SKU :COC23386
AuthorFlorian M Kovar MD,Lukas Poyntner MD and Georg Endler MD univ.Doz.
Number of Pages88
Publishing Year7/18/2010
Edition1 st
Book TypeClinical & internal medicine
Country of ManufactureIndia
Product BrandVDM Verlag Dr. Müller
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-28 00:00:00