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Molecular Targets of Colorectal cancer

 

Marketed By :  Scholars' Press   Sold By :  Kamal Books International  
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  • Product Description
 

This book describes the crucial molecular targets of colorectal cancer. It is considered as a serious health problem in most developed countries and is the third leading cause of cancer mortality throughout the world. Colorectal cancer affects >1 million people every year and is responsible for >.5 million cancer-related annual deaths. Generally it is a multi-step process involving three distinct stages, initiation that alters the molecular message of a normal cell, followed by promotion and progression that ultimately ends up with a phenotypically altered "transformed cell". The concept of multi-stage carcinogenesis involves the sequential acquisition of cellular mutations followed by expansion of the mutated clone within a population of cells. During the development of cancer there are numerous signalling pathways(PI3K/Akt/mTOR, Wnt/β-catenin, Notch, COX-2, iNOS, Apoptosis, JAK/STAT3)were dysregulated. Developing new, effective and less side effect chemotherapeutic drugs are the challenge for researcher's. So, understanding the molecular alterations during colon cancer will enable to develop more chemotherapeutic drugs for colon cancer.

Product Specifications
SKU :COC77511
AuthorAshok Kumar Pandurangan and Norhaizan Mohd. Esa
LanguageEnglish
BindingPaperback
Number of Pages100
Publishing Year2014-06-19T00:00:00.000
ISBN9783639719031
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandScholars' Press
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00