Psoriasis is a long lasting scaling and inflammatory skin disease. Bible and Greeks identified this disease long time before. Psoriasis sufferers in United States population are about three to four percent and near about five million adults of both genders are affected. Psoriasis can be interpreted as a defective reaction of the skin to the injury instead of normal cornification, the cell division rate in the epidermis increases to five times in comparison to its normal level with formation of a pathological stratum corneum. This book will provide a basic guide line in the prevention and cure of the Psoriasis. Silvery white scales erosion seen on the top of the skin needed treatment. Male and female subjects are equally affected at any age. The remedies, diet control, nutritional supplements and certain drugs mention may help to reduce the problem even completely cure the Psoriasis. This book provides latest research, information with regard to the molecular weight of keratin, Genes responsible for this disorder and the amino acids variables present in epidermal keratin of normal and affected skin.