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Molecularly Imprinted Receptor Targeting Lung Cancer Biomarker

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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Rs. 4,835

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  • Product Description
 

The early diagnosis of biomarker is crucial for patient survival and successful prognosis of the disease, and for this reason sensitive and specific methods are required for early cancer diagnosis. However, common techniques for separation and concentrating biomarker are not optimal from the viewpoints of sensitivity and selectivity because analyzing these biomarkers from a small amount of serum is difficult due to the complexity of the sample and low levels of these biomarkers. Peptide imprinted polymers were developed for detection of progastrin releasing peptide (ProGRP); a low abundant blood based biomarker for small cell lung cancer. Peptide imprinted polymers with the best affinity characteristics were first identified from a 96-polymer combinatorial libraries. The effects of monomers, crosslinker, porogen, and template on adsorption capacity and selectivity for nonapeptide sequence NLLGLIEAK resulting from tryptic digestion were investigated and optimized. Ultimately, a solid phase extraction method was developed for highly selective enrichment of the target peptide from tryptic digests.

Product Specifications
SKU :COC77773
AuthorAbed Abdel Qader
LanguageEnglish
BindingPaperback
Number of Pages168
Publishing Year2014-07-15T00:00:00.000
ISBN9783659570155
Edition1 st
Book TypeChemistry
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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