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Monograph on Genomics of Ageing Gene-Sirt1


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Ageing is a syndrome of changes that are deleterious, progressive, universal & thus irreversible. SIRT1 gene is a candidate gene, involved in ageing process. The SIRT1 gene, whose activity is modified by the body's metabolic state & was previously known to help control the process of ageing and extend the lifespan of humans, also plays a key role in regulating the internal clock. This important discovery helps to explain how the body regulates essential functions such as hormone production, body temperature & blood pressure, & may eventually lead to drugs to combat metabolic disorders, obesity or diabetes. SIRT1 gene codes for the protein ?SIRTUINS?. By using Bioinformatics Tools & Softwares Exons, Introns, SNPs & RFLPs of SIRT1 were predicted. SNPs are consequently important in understanding human health. Information related to functional SNPs in candidate disease genes is critical for cost effective genetic association studies, which attempt to understand the genetics of complex diseases. The 3D structure of Sirtuin was modeled & Docked with suitable ligands. The SIRT1 activation study helps in medical application for developing SIRT1 activating drugs for ageing problems.

Product Specifications
SKU :COC99525
AuthorRadha Mahendran,Palani Muthu and Suba Sri
Number of Pages160
Publishing Year2011-10-20T00:00:00.000
Edition1 st
Book TypeGenetics (non-medical)
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-18 00:00:00