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Mucoadhesive Formulation and Evaluation of Terbutaline Sulphate Tablet

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Bioadhesive polymers that bind to the gastric mucin or epithelial cell surface are useful in drug delivery for the purpose of (a) retaining a dosage form in the G.I tract and (b) increasing the intimacy and duration of contact of drug with the absorbing membrane. In this investigation, natural mucoadhesive materials were isolated from different edible fruits like Aegle marmelos (Linn.) Cor., Zizyphus mauritiana and Tamarindus indica by hot extraction method. Density and swelling property of natural materials were evaluated. Bioadhesive and mucoadhesive qualities of natural materials were evaluated individually by different in vitro testing methods and in vivo X-ray photograph method. It was observed that natural materials have good mucoadhesive property. Mucoadhesive tablets containing 7.5 mg of terbutaline sulphate tablets were prepared by wet granulation method. The sustained release pattern was evaluated by in vitro and in vivo studies. The drug release data were plotted using various kinetic equations (zero order, first order, Higuchi’s kinetics.Finally we confirmed our investigation by invitro-invivo correlation study.

Product Specifications
SKU :COC85105
AuthorRanabir Chanda,Saumya Samanta and Pranabesh Chakraborty
LanguageEnglish
BindingPaperback
Number of Pages64
Publishing Year2013-06-26T00:00:00.000
ISBN9783659374005
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00