Aerobiology is the specialized field of investigation had its first development in 1930’s. However the presence of microbes in the atmosphere was detected by the experiment of earlier workers as early in 18th century. Atmospheric pollution is one of the major problems of our age. This pollution has now reached an advance level those possessing a potential threat to the health and well being of the population. Microorganisms are the primary sources of indoor air contamination. The quality of the indoor environment, infectious levels is not easily defined or controlled and can cause various diseases. Musty odor, dampness, water leaks, high humidity and visible mold growth are common indicators that airborne spores are being produced indoors. The type and concentration of fungi in indoor environment is primarily a function of outdoor fungi and humidity level. The concentrations of outdoor fungi and other fungi may be higher due to the occurrence of trees, shrubs and landscape irrigation close to exterior building walls.Since fungal spores and conidia are ubiquitous, the most effective method of source control is elimination of moisture that supports mold growth.