Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The term ’myocardial infarction’, usually known as heart attack, refers to the irreversible necrosis of the heart muscle, resulting from prolonged ischemia, most often caused by plaque rupture with thrombus formation in a coronary vessel. Both intense psychological and physical exertion, among with risk factors such as high blood pressure, stress, smoking, obesity etc. are considered the major causes of the heart attack. Nowadays, it is described as a key issue of death cases in the United States, where more than 1 million people have annually acute myocardial infarctions. Learn more about myocardial infarction, its symptoms and causes in this book.