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Non-Ribosomal Peptide Synthetases in Cyanobacteria


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  • Product Description

Non-ribosomal peptide synthetases (NRPSs) are highly refined natural machines for the biosynthesis of secondary oligopeptides which cannot be synthesised by the ribosomal machinery. Due to the attractive biological potential of many of these secondary metabolites, a great interest to investigate these systems for further exploitation and understanding have taken place in recent years. Because of the relative linear modular structure of NRPSs, they have become potential targets for combinatorial manipulations to reprogram the natural peptides to aid in the discovery of improved and more active peptides. Cyanobacteria are a rich source of these secondary metabolites, and have been found to be one of the oldest living organisms which have developed these biosynthetic pathways. Genetic elucidation of these pathways has been described by a large body of literature for the past two decades; yet there are only a few completely described biosynthetic pathways. Within this work, a method to use inter- adenylation domainal consensus primers to obtain the whole gene cluster with simple molecular techniques is described.

Product Specifications
SKU :COC22529
AuthorTom Inge Sønju
Number of Pages140
Publishing Year8/26/2010
Edition1 st
Book TypeGenetics (non-medical)
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-28 00:00:00
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