Oxidative stress has been forwarded as one of the most important factors detrimental to sperm function and a significant factor in the etiology of male infertility. There is evidence to suggest an association between oxidative stress induced by reactive oxygen species (ROS) and chronic diseases. Antioxidants, by virtue of their ability to mitigate the damaging effects of ROS, have generated interest in their use as chemo preventive agents for a number of chronic diseases. Recent science has witnessed generation of interest in the role of nutraceuticals for the treatment of male infertility. A nutraceutical is a dietary supplement that can aid in prevention and/ or treatmen6t of a disease or disorder. A number of clinical studies have been completed and results of many more are eagerly awaited to define the exact role and place of these agents in therapeutic management of various illnesses. Intake of using a combination of minerals, vitamins and antioxidants has been advocated to improve sperm quality and function.
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