Cholecalciferol or vitamin D3 is a steroid hormone, which is one of the fat-soluble vitamins.
Vitamin D3, as a health supplement promotes bone health and its deficiency leads to weak bones and other body problems
Calcitriol is the active form of vitamin D3, which has a crucial role in the maintenance of potassium and calcium levels in the blood and bone mineralization
Cholecalciferol is an inactive molecule, and it is activated by two hydroxylation reactions. The first hydroxylation reaction happens in the liver in order to synthesize 25-hydroxycholecalciferol from cholecalciferol. The second hydroxylation happens in the kidney, where the 25-hydroxycholecalciferol is converted to 1, 25-hydroxycholecalciferol (calcitriol).
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