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Hepatitis C virus infection


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Hepatitis C Virus (HCV) infects 170 million people worldwide. Current standard treatment with pegylated interferon alpha (IFN?) and ribavirin cures only 50% patients. Therefore, developing a prognostic tool that can be used to predict whether a given patient will respond to therapy is of great importance clinically. This book describes a novel predicting method based on a subset of 18 hepatic gene expression that predicts who will respond to therapy with an accuracy of 96%. A new ubiquitin-like signaling pathway (ISG15/USP18) was revealed to be involved in interferon resistance. Furthermore, preactivation of interferon signaling pathway leading to the increased expression of some interferon stimulated genes (ISGs) in hapatocytes correlates with treatment non-response. Data presented in this book help us understand novel mechanisms of interferon resistance in HCV infected patients. This book should be especially useful to professionals in HCV and personalized medicine field.

Product Specifications
SKU :COC26322
AuthorLimin Chen,Ian McGilvray and Aled Edwards
Number of Pages248
Publishing Year11/17/2012
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-29 00:00:00