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Opening the gates of death: Channels in mitochondria

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Mitochondria are vital cell organelles which sustain cellular life by acting as energy factories in a normal cell. Under certain circumstances, mitochondria turn into the gateways to death by releasing death-inducing proteins into the cytosol. The channels in the mitochondrial outer membrane that allow the efflux of the death-inducing proteins from mitochondria into the cytosol are unknown. My graduate research work was focused on understanding the nature of these channels both structurally and functionally. I discovered that the lipid called ceramide and the protein called Bax act together to facilitate protein release from mitochondria. My work shed further insights into how ceramide forms channels. I also explored the dynamics of channel formation by Bax. I developed ionic strength as a useful diagnostic tool study Bax channel formation in vitro.

Product Specifications
SKU :COC56096
AuthorVidyaramanan Ganesan
LanguageEnglish
BindingPaperback
Number of Pages164
Publishing Year2014-07-18T00:00:00.000
ISBN9783659331329
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-06-08 00:00:00