Many of the opportunistic infections in HIV are caused by commensal bacteria which are otherwise harmless in a normal individual.The study was designed to compare the oral microbiota in normal and HIV infected individuals. The study tries to establish a significant shift in oral microflora in HIV infected patients. Our study is unique in that such a study of the oral commensals in HIV patients has never been reported. We found an increased colonization of the oral cavity by Micrococcus spp. which is a normal commensal of the skin.