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Outcomes after liver transplantation for HCC: a meta-analysis

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

There is growing interest in extending Milan selection criteria for liver transplantation for HCC. We evaluated the impact of different selection criteria, tumour diameter, and number on overall survival (OS), disease-free survival (DFS) and recurrence after liver transplantation. Liver transplantation beyond Milan criteria resulted in decreased OS, DFS, and increased recurrence, similar to transplantation beyond UCSF criteria. Transplantation with summated tumour diameters >10cm or >9cm showed decreased OS, and DFS respectively. The diameter of the largest tumour when >5cm (vs. ?5cm) resulted in decreased OS, DFS, and increased recurrence. Transplantation with >3 nodules resulted in reduced OS. These data suggest that liver transplantation for HCC should be limited to single lesion ?5cm (thus restricted UCSF criteria) or multiple lesions with summated diameters ?9cm (thus validation of Milan criteria), but also suggest expansion of criteria to allow more than 3 nodules if summated diameters ?9cm.

Product Specifications
SKU :COC30141
AuthorGiacomo Germani,Patrizia Burra and Andrew K. Burroughs
LanguageEnglish
BindingPaperback
Number of Pages60
Publishing Year8/14/2012
ISBN978-3659165306
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-29 00:00:00