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Oxidative stress and diabetes on neuronal function and metabolism


Marketed By :  VDM Verlag Dr. Müller   Sold By :  Kamal Books International  
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Rs. 5,886

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  • Product Description

In the last two decades insulin signalling and protection in brain has emerged as a novel field of research.Although growing evidence supports the hypothesis that dysfunction of neuronal glucose utilization and metabolism and/or in insulin receptor signal transduction cascade is involved in Alzheimer’s disease pathogenesis,the role of insulin on oxidative stress- and diabetes-induced neuronal dysfunction and death has been less investigated.This book,therefore,provides new experimental evidences that reveal the cascade of events underlying the putative neuroprotective effect of insulin on neurotransmission,and neuronal function and survival associated with oxidative stress and diabetes.More specifically,it is shown that insulin has a neuromodulatory role,and also that it activates neuronal receptor-mediated signalling,controlling antioxidant defences,glucose metabolism and preventing against apoptosis associated with oxidative stress.Herewith,we can find valuable tools (especially to Neuroendocrinologists,Neurochemists and Pharmacologists) to establish insulin as a promising therapeutic agent,particularly in normoglycemia conditions.

Product Specifications
SKU :COC39419
AuthorAna Duarte
Number of Pages276
Publishing Year2010-04-02T00:00:00.000
Edition247 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandVDM Verlag Dr. Müller
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-01-08 00:00:00