Bangladesh is a land of rivers and ponds and notable for being a fish-loving nation, acquiring the name "Machh-e Bhat-e Bangali" which means, "Bengali by fish and rice". Most of the people in the developing countries specially in Bangladesh are dependent on fish as a source of animal protein. It has been estimated that about 80% of the animal protein in our diet comes from fish alone. In addition,Pangasius pangasius and Pangasius sutchi are fresh water fish species of Bangladesh which are extensively used as a common fish by our local peoples. In Bangladesh, these fish species are known as “River Pangas” and "Pond Pangas" respectively. From this point of view, we try to investigate the different fatty acid compositions and nutrients status of these fishes due to enrich the acceptability as the nutritious fish for our populations.