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Parkinson's disease: Biochemical and Genetic Perspectives

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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Rs. 2,675

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  • Product Description
 

Parkinson's disease (PD) is a chronic neurological disorder which characterized by loss of nigrostriatal dopaminergic neurons. Current drugs only provide symptomatic relief and manage the stop the death of dopaminergic neurons. Developments of therapies for neurological diseases are limited and complex. The many case of PD are sporadic, genes mutation which associated with rare familial forms of the disease that code α - synuclein, parking, DJ- 1, PINK - 1 and LRRK2. The relationship between UPS and neurodegeneration has been strengthened with the discovery of mutations in the gene that codes for ubiquitin-proteasome pathway proteins in PD. Discovery of this gene and experimental studies in animal models provide insight into important molecular mechanisms in the pathogenesis and identify potential targets for treatment. Also mitochondrial dysfunction, oxidative damage, abnormal protein aggregation and protein phosphorylation are essential in the pathogenesis of both sporadic and familial.signal transfer between different cell type and their effects are important to better understanding of cause of disease.

Product Specifications
SKU :COC77529
AuthorMaryam Chinisaz and Robab Sheikhpour
LanguageEnglish
BindingPaperback
Number of Pages60
Publishing Year2014-10-01T00:00:00.000
ISBN9783659612916
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00