Seaport container cranes are highly vulnerable to natural disasters such as earthquakes and severe windstorms. Damage to container cranes affects the functionality of seaports in terms of economic loss due to repair/ replacement and downtime. In addition, it may accrue considerable amount of business loss owing to permanent traffic rerouting. Although a significant number of wind-induced failure of container cranes have been reported, literature related to cause of such failures is inadequate. This document provides an approach for systematic investigation of response of seaport container cranes under wind loading. Emphasis is placed on estimating the effect of structural configurations and stochastic of wind field on failure vulnerability of modern-day sea container cranes. The failure vulnerability of container cranes has been estimated by means of fragility analysis with respect to different parameters such as boom positions, yaw angle, gradient height, and gradient wind speed. Also introduced are the Monte Carlo simulation and sensitivity analysis for probabilistic assessments of performance. Finally, a few relevant research needs in this area have been identified.