Call Us 080-41656200 (Mon-Sat: 10AM-8PM)
Free Shipping above Rs. 1499
Cash On Delivery*

Persistent T-cell activation: A therapeutic option for alopecia areata


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days


Check Your Delivery Options

Rs. 5,886

Availability: In stock

  • Product Description

Alopecia areata is a T-cell mediated autoimmune disease which mainly affects the anagen stage hair follicles, the most effective way of treating alopecia areata is the application of contact sensitizers which induces a mild chronic eczema (delayed type hypersensitivity). The curative effect of chronic eczema relies on the expansion of myeloid derived suppressor cells (MDSC) which can suppress the autoreactive T-cells and induces apoptosis of these via mitochondrial apoptotic pathway. Alternatively, a blockade of accessory molecules in T-cell activation could possibly be of therapeutic benefit. CD44 and CD49d being candidate accessory molecules since association of CD44 with CD49d plays an important role in homing of lymphocytes and blockade of these bystander pathways could be a therapeutic approach in alopecia areata.

Product Specifications
SKU :COC97838
AuthorVibhuti Singh
Number of Pages216
Publishing Year2011-11-01T00:00:00.000
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-18 00:00:00