The personality of a political leader had remained a major issue of discussion among scholars because the personality of a leader has importance in the foreign policy decision-making process of a developing country South Asian Politics. The importance of examining the Benazir Bhutto’s personality and her impact on Pakistan’s foreign policy is much more signified by the fact that she is recognized as a leader at the national as well as the international level. Benazir Bhutto’s personality is a mixture of varied personality traits. She is determinant and skillful lady. She has command over crises management which can be shown at the time when Pakistan’s relations were on the stack. Pakistan’s relations with the United States occupy important place in Pakistan’s foreign policy. The two states have generally maintained favorable dispositions towards each other, but their interaction has not always progressed smoothly. Pak-US Relations and the significant issues involved between them during her both terms in office had been examined in details. It is tried to asses that to what extent her personality contributed towards relations between Pakistan and the US.