The book entitled “Pharmacological properties of the medicinal plant Coccinia grandis L. Voigt. With Special Emphasis On Oxidative Stress”. The plant material consists of dried powder leaves of C.grandis L. Voigt. Majority of the disease or disorders are mainly linked to oxidative stress due to free radicals. Free radicals are fundamental to any biochemical process and represent an essential part of aerobic life and metabolism. Production of free radicals in the biological system results the imbalance in the level of pro-oxidant and anti-oxidant known as Oxidative stress. This book highlights information on synonym, vernacular names, distribution, parts used, extraction process, in vitro & in vivo pharmacological activities and phytochemical analysis. This book consists of several chapters. This book will be very useful to the under graduate and post graduate students of Pharmacy, Pharmacists, Pharmacologists, Medicinal Chemists, Toxicologists, Pharmacognosists and Botanists. Common people will also get interest about this book. It is a handbook to read, keep and refer to again and again.