AMC for osmotic release deals with the various aspects of Phase Transited System with emphasis of research work being on Asymmetric Membrane Capsule (AMC). In- depth analysis of these systems have been reported. Readers will particularly find it interesting on the correct methods involved for UV detection. For eg. to force the regressed line through zero or to take an intercept. More interesting are the readings of in-vivo and in-vitro correlation methods.