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Phytochemical and Biological Investigations of Thunbergia grandiflora

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Thunbergia grandiflora(Acanthaceae) has been investigated for isolation of its secondary metabolites and evaluation of biological activities of the crude extractive. One compound had been isolated, which was identified by extensive analyses of resolution NMR spectral data. The powdered leaf of T. grandiflora was extracted separately with methanol. The solid extract was then subjected to vacuum liquid chromatography (VLC). Repeated chromatographic separation and purification the leaves of Thunbergia grandiflora afforded one flavonoid named 5 hydroxy-4’,6,7- trimethoxy flavone, C18H16O6. The Methanolic crude extract of Thunbergia grandiflora showed moderate analgesic activity. Out of all the samples only chloroform fraction methanolic crude extract were appeared mild potent in terms of both zone of inhibition & spectrum of activity against some gram positive, gram negative bacteria and fungi. In antidiarrhoeal test and brine shrimp lethality bioassay , hexane, carbon tetrachloride, chloroform and aqueous fractions exhibited insignificant activities whereas Carbon tetra chloride fraction showed some hypoglycemic effect at a dose of 300 mg/kg body weight compared to control group.

Product Specifications
SKU :COC31212
AuthorAszadur Rahman Chowdhury,K. M. Shams-Ud-Doha and Kh. Tanvir Ahmed
LanguageEnglish
BindingPaperback
Number of Pages112
Publishing Year1/17/2012
ISBN978-3847313335
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00
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