PLG-CpG microencapsulated rPolyprotein and inactivated 146'S' FMDV


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Foot and mouth disease virus (FMDV) cause one of the major scourge of the livestock industry affecting cloven-hoofed animals, causing tremendous economic losses. Infection occurs mainly through mucosal route; thereby stressing the importance of mucosal vaccination as one of the first steps in prevention and control. This study described a potential mucosal vaccination system for immunoprophylaxis against the disease by adopting an experimental approach in microencapsulation of inactivated 146‘S’ whole virus and recombinant FMDV polyprotein expressed in E.coli along with CpG ODN as a co-adjuvant in a poly (DL-lactide-co-glycolide) delivery system. The formulation was found to be an effective mucosal as well as systemic adjuvant and an efficient antigen delivery system. This study observed the possibility of using this novel preparation to elicit appreciable level of protection against FMDV at the mucosal, humoral and cellular level.

Product Specifications
SKU :COC85254
AuthorRinmuanpuii Ralte
Number of Pages132
Publishing Year2013-01-25T00:00:00.000
Edition1 st
Book TypeVeterinary medicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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