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PNA : Potentially better alternative for on-surface DNA detection

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 
Peptide Nucleic Acid (PNA) is an alternative nucleic acid, capable of sequence-specific binding with complementary DNA with higher affinity compared to DNA, which is reflected in the higher melting temperature value for PNA-DNA duplexes compared to that for DNA-DNA duplexes. It is this property of PNA that makes this molecule a potentially better alternative than DNA in nucleic acid detection technologies. Though the DNA SAMs have been applied in the micro scale as well as nanoscale nucleic acid sensing experiments, the problems of lack of sensitivity and reproducibility persist, probably because of defects in the generally disordered DNA films. In the present study, the effectiveness of ssPNA strands as sensor probes for on-surface DNA detection has been tested.
Product Specifications
SKU :COC5560
AuthorSrabani Ghosh
BindingPaperback
Number of Pages232
Publishing Year04/09/15
ISBN9.78E+12
Edition1st
Book TypeBIology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece (Paperback)
Product First Available On ClickOnCare.com2015-06-24 00:00:00