The development and designing of polymeric reagents to suites the growing demands in the field of synthesis is certainly one of the most exciting and spectacular topics in contemporary organic chemistry. Recent outburst in the use of polymeric reagents is mainly due to the ease of purification of the reaction mixtures. Unlike their soluble counterpart which requires tedious traditional purification process, solid phase synthesis involves an easy purification process i.e simple filtration. Synthesis using polymeric reagent facilitated easy automation and an excess reagent could be used to bolster a faster reactions. It has also been established that reactions performed in solid phase synthetic pathway are less moisture sensitive due to highly hydrophobic polymer backbone. The ease of recycling and re-usability of the polymer and the simplification of handling a range of toxic or odorous materials added the advantage of using polymeric reagents. Furthermore, this technique addresses problem of polymerization since polymer beads are discrete and reaction between two polymer beads are impossible. Hence, polymer-supported reagents and molecules tend to react intramolecularly.