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Potential HIV Reverse Transcriptase Inhibitors

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

The existence of CNS viral reservoirs is the main cause of recurrence of HIV infection after medication is withdrawn. This problem remains unsolved because of poor CNS penetration with the existing anti retroviral drugs. To meet the demand of crossing the blood-brain barrier (BBB) the compound should have polar surface area (PSA). PSA is defined as the surface area occupied by oxygen and nitrogen atoms and hydrogen atoms attached to these atoms. With this aspect in view, we calculated the PSA values of various substituent on the aryl rings in our aimed compounds and they were found within the prescribed limits so we proceeded with the synthesis of the compounds.

Product Specifications
SKU :COC31280
AuthorKomal P. Patel,Jimish R. Patel and Rajani Giridhar
LanguageEnglish
BindingPaperback
Number of Pages68
Publishing Year7/14/2012
ISBN978-3659184710
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00
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