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PPI-Filter :a framework for Protein-Protein Interactions prediction

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Protein-protein interaction (PPI) is at the center of most cellular processes from DNA replication to cell motility. Although experimental approaches have limitations that can be complemented by the computational methods, the results from computational methods still suffer high false positive rates which contributed to the lack of solid PPI information. Therefore, this work proposed a computational framework to reduce the false positive pairs in PPIs prediction and at the same time sustaining the true positive pairs by using information based on three different genomic features: i) annotation information feature that incorporates Gene Ontology Annotation (GOA); ii) sequence feature that incorporates homologous interactions; and iii) structure feature that incorporates Protein Families (PFAM) domain interactions. This book could be useful to the professional biologist, to the academic community such as in the field of computer or bioinformatics in which could shed some light about utilizing biological data using the techniques and theories of computer sciences to accelerate findings in the biomedical world.

Product Specifications
SKU :COC18221
AuthorRosfuzah Roslan
LanguageEnglish
BindingPaperback
Number of Pages108
Publishing Year1/25/2012
ISBN978-3847374114
Edition1 st
Book TypeComputer networking & communications
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-27 00:00:00