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Prediction of Catalytic Residues in Protein Active Site by SVM


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

In this study,prediction of physiochemical properties of catalytic sites residues using a suitable Artificial Neural Networking (ANN) Backpropagation algorithm coupled with a set of structural proteins with the properties of their amino acid residues. The method has been applied to a set of 100 structural proteins from the Protein Data Bank (PDB.Using Ligplot program for searching of active site residues the identified amino acid residues were classified in 15 different categories based on their physiochemical properties. After classification of active and non active site amino acids, their properties were converted into machine language. Furthermore, we created Neural Network Using Matlab software and generated algorithm for training and testing of data. Thereafter, analysis of results showed that 95% of active site’s physiochemical properties were correctly predicted. It is hoped that this work would help in determining the surface topographic properties for ligand binding sites residues in protein. The computational outcome would be helpful in ligand designing,and structural identification and functional sites Comparison.

Product Specifications
SKU :COC36698
AuthorBRIJESH YADAV and Pritish Varadwaj
Number of Pages80
Publishing Year1/31/2012
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-02-08 00:00:00