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Preparation and Characterization of Prednisolone Loaded Microsponges

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

In this research work, modified microsponges have been developed that release drug in controlled manner and enhance the bioavailability of drug. This study presents a novel colon specific drug delivery system containing prednisolone. Colon targeting is naturally of value for the topical treatment of diseases of colon such as chron’s disease, ulcerative colitis, colorectal cancer, and amebiasis. It is also valuable for the oral delivery of drugs unstable or susceptible to enzymatic degradation in upper G.I.T. tract. The advantages of targeting drug to specifically to the diseased colon are reduced incidence of systemic side-effects, lower dose of drug, supply of the drug to the biophase only when it is required and maintenance of the drug in its intact form as close as possible to the target site. That’s why improved drug delivery system is required for drugs currently in use to treat localised disease of the colon. It has been concluded that obtained microsponges work as a best dosage form for colon targeting due to good mucoadhesion property and more retention time in the colon. Microsponges based drug delivery would play a beneficial role in future clinical purposes.

Product Specifications
SKU :COC76813
AuthorSonali Singh,Sunil Kumar Prajapati and Rahul Pratap Singh
LanguageEnglish
BindingPaperback
Number of Pages136
Publishing Year2014-10-20T00:00:00.000
ISBN9783659593109
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00