Lipase is an catalyzing and hydrolyzing enzyme which is of vital importance in digestion and processing dietary lipids. Lipase has surfaced as one of the leading biocatalysts contributing to the multibillion dollar subjugated lipid technology bio-industry and has been used in comprehensive industrial application. Interest in lipase has amplified distinctly in the last two decades given to their applications in oleo chemical detergent, organic industries, leather industry, environmental management, cosmetics and perfume industry, biomedical and biosensors. A growing interest in SSF for lipase production has been observed in recent years. This production can be optimized by varying the physical and chemical factors which are essentially maintained during its production.