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Production Enhancement of Cyclosporin ''A'' through Mutation


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  • Product Description

Cyclosporin ?A'' is the major component of the Cyclosporins, a group of nonpolar cyclic oligopeptides possessing immunosuppressive activity. Cyclosporin ?A'' is used extensively in the prevention and treatment of graft-versus-host reactions in bone marrow transplantation and for the prevention of rejection of kidney, heart, and liver transplants. As its role in transplantation surgery increases, the demand on industry to improved yields intensifies. In order to obtain and maintain a competitive economic position for new and existing fermentation respectively, it is also necessary to find means for increasing the yields of the fermentation product. The present study has been designed to enhance production capability of Cyclosporin ?A'' by local isolates of Aspergillus terreus by mutating the cultures with UV radiation and mutagenic chemicals.

Product Specifications
SKU :COC97370
AuthorWajiha Iram and Tehmina Anjum
Number of Pages112
Publishing Year2011-07-24T00:00:00.000
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandNot defined
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-18 00:00:00
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