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Prognostic factors in malignant melanoma


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Malignant melanoma is one of the most malignant types of skin cancer. Incidences are on the rise worldwide.Early detection and early surgical removal are associated with reduced mortality.The strong aggressiveness of this malignant disease is caused by its local invasive growth and tendency to metastasize early. Malignant melanoma is highly metabolically active tumor that releases a number of enzymes, cytokines, growth hormones and other molecules. The aim of this work was to determine the usability of preoperative and postoperative serum and plasma levels of biomarkers in primary diagnosis of tumor activity and in the postoperative follow-up care. We measured circulating levels of several biomarkers in a group of 77 patients with malignant melanoma and cohort of 34 patients without cancer as a control group. Using routine immunoassays and novel multiplex xMAP technology, we measured: thymidine kinase, tissue polypeptide specific antigen, protein S100A, osteoprotegerin, osteopontin , insulin-like growth factor binding proteins 1 and 3, epidermal growth factor, interleukin -2, -6, -8, -10, vascular endothelial growth factor.

Product Specifications
SKU :COC60450
AuthorInka Treskova
Number of Pages120
Publishing Year17.04.2014
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-05 00:00:00
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