Pyrrolo-benzodiazepine class of Privileged Medicinal Scaffolds


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  • Product Description

On account of the wide range of the biological properties displayed by benzodiazepine derived compounds, benzodiazepine scaffold have been considered among the most important privileged structures for drug discovery. The development of novel biological materials based on the privileged structure is an intense area of research. Global efforts are underway to develop chemotherapeutic agentsThe main thrust of work in the area of additional fused heterocyclic rings is stimulated by the isolation of a series of antitumor antibiotics such as anthramycin, sibiromycin, tomaymycin, prothacarin, chicamycins A,B and neothramycins A,B (to mention a few), from the pyrrolo[2,1-c][1,4]-benzodiazepine class of compounds These biosynthetically derived materials are well known for inhibiting DNA replication on account of the formation of DNA – antibiotic adduct .

Product Specifications
SKU :COC95080
AuthorSumitra Nain,Prof. D. Kishore and Prof. B. P. Nagori
Number of Pages76
Publishing Year2011-08-02T00:00:00.000
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-14 00:00:00
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