To study the performance of Tuned Liquid Column Damper (TLCD) the formulation of structure-TLCD combined system considers mass, damping and stiffness of primary structure and damper parameters like mass ratio, tuning ratio, length ratio, damping in terms of head loss coefficient of the orifice installed in TLCD. The maximum structural displacement obtained from the parametric study is used as the objective function for the optimization process to get optimum TLCD and the liquid displacement inside the damper. This optimum TLCD is further used to calculate the acceleration to check for any potential problem. For this optimization process a set of real seismic records are considered having wide range of intensity, dominant frequency and duration. Furthermore, a statistical study is performed to understand the possible variations in the performance of TLCD. The observations of the parametric analysis and optimization results are in conformity with the fact that TLCD performs well in case of structural displacement reduction. But, in case of structural acceleration reduction, it is not performing well, even in some cases it shows negative results.