A qualitative approach which is exploratory in nature was used to explore retention of nurses in Ghana: perspectives of nurses at Korle-Bu Teaching Hospital. The research sought to explore what had made nurses stay in Ghana and what these nurses believe will enhance retention of nurses in Ghana. Eleven participants were interviewed including a nurse administrator. The inclusion criterion was nurses who had worked in Ghana for at least ten years. The analytic strategy was content analysis and after verbatim transcription, checking correcting and coding personal convictions, monetary benefits and improved working conditions were found to be the reasons why nurses had been retained in Ghana. Personal convictions should be exploited in order to retain nurses. The Ghana Registered nurses Association should ensure that nurses are well paid, this they can do by lobbying and the Ministry of Health should improve upon the working conditions of nurses.