Copper and Zinc are essential trace elements required for the normal human well being. They play a significant role by amplifying the full function of the larger molecule of which they are a part and are specific to particular functions like in the immune system of the body. They form a part of various essential proteins and enzymes and any excess or deficiency can lead to various disease states in humans. Current studies have shown their role in numerous oral conditions like oral cancer and oral submucous fibrosis. Knowledge of these essential elements is therefore very important for medical, dental and paramedical professionals.This book provides an insight into the physiological and clinical importance of these two micro-nutrients.