Safe sex behaviors towards HIV/AIDS among Myanmar migrants of reproductive aged population in Samutsakhon Province, Thailand were assessed as a cross-sectional study in 2008. Their socio-demographic characteristics, knowledge, perception and cue to action on HIV/AIDS as well as their safe sex behaviors were found out.Safe sex behaviors in this study are no sex with unknown partner,intention of faithfulness to spouse or partner, intention to use condom and consistent condom use.Out of 260 respondents, 69.6% are in moderate level behavior,15.4% in good and 15.0% in poor level. Consistent condom use is 55.8%.Data analysis shows that there were relationship between age, gender,educational level, marital status, occupation, knowledge level, perception level, media, influencing person, experience of seeing AIDS patient factors and safe sex behavior.Health personnel are the most influencing person. Continuation of health education and workplace condom promotion program should be encouraged more. Joint cooperation of local authorities,provincial health office and NGOs must be appreciated more.A further in-depth qualitative study about safe sex behaviors among them should be done.