Scientific instrumentation underlies an enourmous variety of devices present in daily life as well as in sophisticated apparatus developed for scientific research and technological applications. The impact of the developments in this field are more and more visible, reaching levels hardly imaginable few decades ago. A comprehensive collection of relevant information for the beginner and even for the professional in the field may be difficult to find, since it is spread over many specialized textbooks and articles. This book is precisely an important compilation of the available knowledge contributing to the activity in the area, written by renown experts. The graduated or undergratude student, high school and university teachers, engineers and physiciens will be delighted to learn from it details concerning fundamental particles interactions, particle detection techniques, x-ray image acquistion and treatment, high speed electronics, signal processing and much more.