Long term care for people with chronic illnesses and disabilities is a pressing issue globally. As demand for long term care increases, the assumption that extended family networks can meet all the needs of their members deteriorates. Caregiving can be a rewarding service to families and the community at large, however it has it’s challenges; Caregiving burden and risk to one’s own health. This book explores factors influencing practice of self care among caregivers of people living with HIV and AIDS (PLWHAs) as well as their practice of self care thereby providing a foundation for improved health status among caregivers of chronically ill persons. It also acts as a start point for policy makers in the area of caregiving.