The most important idea of this book is that currently, the therapy of the patients with chronic viral B or C hepatitis remain yet a problem open for research because the solution for these patients is far from being found. This book contains many clinical cases from my medical practice about the most important side effects of therapy with Interferon and Ribavarin on patients with active chronic hepatitis with virus B or C positive. The conclusion is that the principle side effects of this therapy are more dangerous compared to the benefits and this is the reason that I believe with strong opinion that in the future this therapy needs to be substituted with other drugs. The balance between the risks and benefits should be seriously taken into account. This therapeutics protocols must be reevaluated in the medical practice for the benefit of our patients.