The complexity and dynamic behaviour of advanced manufacturing systems, make simulation modelling one of the most popular methods to facilitate the design and assess operating strategies of these systems. The growing need for the use of simulation is reflected by a growth in the number of simulation languages and data-driven simulators in the software market. This research monograph investigates which characteristics typical manufacturing simulators possess, and how the user requirements can be better fulfilled. A comprehensive evaluation framework and methodology for simulation software selection are developed. An application of this methodology could help users to select appropriate simulation packages and avoid costly delays in simulation projects.