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Smoking and Abdominal Aortic Aneurysm


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Abdominal aortic aneurysm (AAA) is an increasingly common vascular disease affecting 2-9% of elderly people aged more than 65 years. Smoking has been considered an important risk factor associated with AAA development but the pathophysiological mechanisms which underly its adverse effects are uncertain. This project confirm previously reported AAA pathological characteristics namely a decrease in number of elastic lamellae, increased macrophage infiltration, decrease in VSMC density and increase of activity of proteases (MMP-2, MMP-9, MMP-12 and elastase). Cigarette smoking however, was associated with an increasing degree of elastin breakdown, macrophage infiltration and extent of MMP-12 activity in the aortic wall as well as increased plasma MMP-2 and elastase levels. The results support a direct relationship between the level of smoking and the extent of aneurysm aortic wall damage.

Product Specifications
SKU :COC30065
AuthorAbdelkader Moussa,Maria Nataatmadja and Malcolm West
Number of Pages96
Publishing Year6/15/2012
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-29 00:00:00