Estimated cost of household ….it was estimated that household paid an average of 20.46 birr ($1.24) for prevention and 119.91 birr ($7.27) for treatment per episode direct cost or out of pocket payment for prevention and treatment of malaria..… the indirect cost for productive days lost and hours wasted for seeking treatment valued 99.50 birr ($6.03) per victim and 22.78 birr per caretaker. Estimation cost of Public Health Institutes; Health Office spends 1.33birr ($0.09) per household for malaria prevention and Health Facilities spend 47.27 birr ($2.87) per victim for treatment. Households’ response towards the disease affects their social matter….17% of households respond, due to the fear of decrease number of children in their households by malaria mortality they bear more children than they plan; …. 3.99% students were reported withdraw among the enrolled in 2010/2011 in Sidama Zone, among other reasons 3% withdrawal were due to malaria. It can be concluded that, malaria have the tendency to affect the long run human capital accumulation by causing school absenteeism. Generally, malaria poses huge economic and social cost on households and health facilitates.